Published: Front Vet Sci. 2016 Dec 14;3:112. doi: 10.3389/fvets.2016.00112. eCollection 2016.
Keyword: adipose-derived progenitor cells; anterior cruciate ligament tear; bone marrow aspirate concentrate; cranial cruciate ligament tear; mesenchymal stem cells; platelet-rich plasma; regenerative therapy
Author(s): "Canapp SO Jr, Leasure CS, Cox C, Ibrahim V, Carr BJ"
Summary: This study was designed to evaluate outcomes in 36 dogs with a partial cranial cruciate ligament (CCL) tear treated with autologous bone marrow aspirate concentrate (BMAC) or adipose-derived progenitor cells (ADPC) with platelet-rich plasma (PRP) combination. The results of this study indicate that the use of BMAC-PRP and ADPC-PRP shows promise for the treatment of early partial CCL tears in dogs. Further studies are needed and should be randomized, blinded, and controlled.